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Original research
Effectiveness of universal school-based mindfulness training compared with normal school provision on teacher mental health and school climate: results of the MYRIAD cluster randomised controlled trial
  1. Willem Kuyken1,
  2. Susan Ball2,
  3. Catherine Crane1,
  4. Poushali Ganguli3,
  5. Benjamin Jones2,
  6. Jesus Montero-Marin1,4,
  7. Elizabeth Nuthall1,
  8. Anam Raja1,
  9. Laura Taylor1,
  10. Kate Tudor1,
  11. Russell M Viner5,
  12. Matthew Allwood1,
  13. Louise Aukland1,
  14. Darren Dunning6,
  15. Tríona Casey1,
  16. Nicola Dalrymple1,
  17. Katherine De Wilde1,
  18. Eleanor-Rose Farley1,
  19. Jennifer Harper1,
  20. Verena Hinze1,
  21. Nils Kappelmann1,
  22. Maria Kempnich1,
  23. Liz Lord1,
  24. Emma Medlicott1,
  25. Lucy Palmer1,
  26. Ariane Petit1,
  27. Alice Philips1,
  28. Isobel Pryor-Nitsch1,
  29. Lucy Radley1,
  30. Anna Sonley1,
  31. Jem Shackleford1,
  32. Alice Tickell1,
  33. MYRIAD Team1,
  34. Sarah-Jayne Blakemore7,8,
  35. Obioha C Ukoumunne2,
  36. Mark T Greenberg9,
  37. Tamsin Ford10,
  38. Tim Dalgleish6,
  39. Sarah Byford3,
  40. J Mark G Williams1
  1. 1 Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK
  2. 2 NIHR Applied Research Collaboration Southwest Peninsula (PenARC), University of Exeter, Exeter, Devon, UK
  3. 3 King’s College London, King’s Health Economics, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, London, UK
  4. 4 Teaching, Research and Innovation Unit, Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Spain
  5. 5 Population, Policy & Practice research programme, UCL Great Ormond St. Institute of Child Health, London, UK
  6. 6 Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK
  7. 7 Department of Psychology, University of Cambridge, Cambridge, UK
  8. 8 UCL Institute of Cognitive Neuroscience, London, UK
  9. 9 Department of Human Development and Family Studies, Pennsylvania State University, Pennsylvania, Pennsylvania, USA
  10. 10 Department of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK
  1. Correspondence to Professor Willem Kuyken, University of Oxford Department of Psychiatry, Oxford OX3 7JX, UK; willem.kuyken{at}


Background Education is broader than academic teaching. It includes teaching students social–emotional skills both directly and indirectly through a positive school climate.

Objective To evaluate if a universal school-based mindfulness training (SBMT) enhances teacher mental health and school climate.

Methods The My Resilience in Adolescence parallel group, cluster randomised controlled trial (registration: ISRCTN86619085; funding: Wellcome Trust (WT104908/Z/14/Z, WT107496/Z/15/Z)) recruited 85 schools (679 teachers) delivering social and emotional teaching across the UK. Schools (clusters) were randomised 1:1 to either continue this provision (teaching as usual (TAU)) or include universal SBMT. Data on teacher mental health and school climate were collected at prerandomisation, postpersonal mindfulness and SBMT teacher training, after delivering SBMT to students, and at 1-year follow-up.

Finding Schools were recruited in academic years 2016/2017 and 2017/2018. Primary analysis (SBMT: 43 schools/362 teachers; TAU: 41 schools/310 teachers) showed that after delivering SBMT to students, SBMT versus TAU enhanced teachers’ mental health (burnout) and school climate. Adjusted standardised mean differences (SBMT minus TAU) were: exhaustion (−0.22; 95% CI −0.38 to −0.05); personal accomplishment (−0.21; −0.41, −0.02); school leadership (0.24; 0.04, 0.44); and respectful climate (0.26; 0.06, 0.47). Effects on burnout were not significant at 1-year follow-up. Effects on school climate were maintained only for respectful climate. No SBMT-related serious adverse events were reported.

Conclusions SBMT supports short-term changes in teacher burnout and school climate. Further work is required to explore how best to sustain improvements.

Clinical implications SBMT has limited effects on teachers’ mental and school climate. Innovative approaches to support and preserve teachers’ mental health and school climate are needed.

  • Child & adolescent psychiatry
  • Depression & mood disorders

Data availability statement

Data are available upon reasonable request. The baseline data and codebook from the MYRIAD trial are available from Prof. Kuyken ( upon request (release of data is subject to an approved proposal and a signed data access agreement).

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See:

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Key messages

What is already known on this topic

  • There are meta-analyses demonstrating the effectiveness of mindfulness-based programmes (MBPs) on mental health in a range of populations and contexts, including school teachers in the educational sector. However, these studies are compromised by sample size and design, including inadequate consideration of the MBP curriculum, teacher engagement, outcome assessment over longer periods and publication bias, nor effects on wider school climate.

What this study adds

  • This study included careful consideration of the MBP itself, fidelity, teacher engagement, follow-up at 1 year, as well as measures of school climate. It suggests that school-based mindfulness training reduced teachers’ burnout and enhanced some dimensions of school climate, but that these effects largely wash out over time.

How this study might affect research, practice or policy

  • MBPs can improve teacher’s mental health in the short term and may also improve school climate. The next generation of research needs to consider how best to support teacher mental health and school climate in sustainable ways and what role MBP might play in this by paying close attention to contextual and implementation factors.


There is a growing consensus that the purpose of schools extends beyond academic teaching, to a social–emotional education that prepares young people for life.1–3 Schools can develop young people’s social–emotional–behavioural competencies directly through teaching social–emotional learning (SEL) curricula,4 and indirectly through a positive school climate.5 School climate is a broad multidimensional term that includes perceptions of different aspects of the school experience in terms of academic, community, safety and structural features. It refers to all aspects of school life, for example, leadership, teaching/learning, professional development, partnership, relationships, connectedness, respect, social/emotional/physical safety, discipline, the school environment, organisation and facilities.5 6 There is promising evidence that a more positive school climate is associated with students’ improved mental and physical health, less absenteeism, better behaviour, less substance use and better academic outcomes.5 7

Teaching can be both rewarding and stressful, as many aspects of teaching are demanding: workload, inspections, high expectations from school senior leadership and parents, students’ behavioural/emotional problems, societal issues that inevitably affect schools (eg, deprivation, discrimination, inequality) and changing educational policies and priorities.8 As a consequence, teacher stress, burnout and absenteeism are common, and there is a high turnover in the teaching profession.9 As such, there are good reasons for schools to safeguard and promote teachers’ mental health.

SEL programmes are focused on helping individuals manage their emotional states, reach goals with empathy for others, maintain positive relationships and make responsible decisions.4 These programmes can enhance both school climate and teachers’ mental health in a range of ways, for example, effective SEL can promote better behaviour among students and effective classroom management, supporting teachers’ self-efficacy, which in turn improves stress, job satisfaction and retention.10–13

One approach to SEL that has shown promise is mindfulness training (MT). School-based mindfulness training (SBMT) delivered by teachers typically involves teachers learning mindfulness themselves, followed by training in how to deliver MT to students, before going on to deliver MT to students. MT involves learning attentional control, and emotional and social regulation that can enhance resilience in the face of stressors, and promote mental health. Systematic reviews suggest positive effects of MT on both young people’s14 and teachers’ mental health.15 Most studies are preliminary and of inconsistent quality, especially with regards to lack of statistical power, unclear specification of the intervention, inadequate or no measurement of intervention fidelity, weak choice of comparator and short follow-up. In addition, there is almost no research on the effects of SBMT on school climate.16

This study is part of a larger programme of work examining the effectiveness, cost-effectiveness, mechanisms, scalability and implementation of SBMT (‘MYRIAD: My Resilience in Adolescence’).17–19


This paper addresses the MYRIAD trial’s secondary question: Is universal SBMT more effective than teaching as usual (TAU) in supporting teachers’ mental health and school climate? An ancillary aim was to examine teachers’ engagement with their personal MT and with SBMT, and whether this engagement was associated with teachers’ mental health and school climate.


The trial was reported in accordance with the Consolidated Standards of Reporting Trials guidelines for cluster randomised controlled trials (RCTs).20 The study design and procedures are presented in full in the published trial protocol17 and update describing study enhancements and adaptations.18

Study design and participants

We used a cluster RCT design, with schools (clusters) as the unit of randomisation, comparing SBMT and TAU, with regard to teachers’ mental health and school climate. All mainstream schools (ages 11–16) in the four UK regions (England, Northern Ireland, Scotland and Wales) were eligible if they had a substantive appointed headteacher, had not been judged inadequate in their most recent official inspection (to mitigate any difficulties in trial implementation) and had a strategy/structure in place for delivery of adequate SEL curricula. Consent was sought at the school level by the corresponding headteacher and by all involved teachers. Both were obtained before randomisation. We recruited schools (n=85) in the academic years 2016/2017 (cohort 1; K=13) and 2017/2018 (cohort 2; K=72).

Prior to randomisation, all study schools nominated up to 15 teachers, normally on substantive contracts to minimise attrition. The headteachers agreed to enable their nominated teachers to participate in the research, complete their personal MT and SBMT teacher training and deliver the SBMT curriculum to students should their school be randomised to the intervention arm. Although up to 15 teachers started the personal MT, a maximum of 5 could go on to training in the SBMT curriculum, and only a subset of those would actually deliver it to students.

TAU schools offered SEL in a wide variety of ways, and the participating study teachers were not necessarily involved in this delivery. Teacher recruitment and attrition across both trial arms are described in figure 1. Teacher selection within the SBMT arm is described in figure 2. Due to the nature of SBMT, teachers were not blind to intervention allocation. The trial data file was cleaned, locked and signed-off by the Trial Steering and Data Monitoring Committees before the statistician was unblinded.

Figure 1

Consolidated Standards of Reporting Trials from diagram for trial schools and teachers. ‘Missing’ is the number of schools (K)/teachers (n) that did not provide data on any of the outcomes at the subsequent timepoint. Teachers could be temporarily lost to follow-up if not in school for a given timepoint. Six hundred seventy-nine teachers in total were recruited, but seven were from a school which dropped out. So only 672 teachers were available for analysis. *None of the teachers at one school provided any follow-up data at the postintervention timepoint. However, teachers from this school provided data at the 1-year follow-up. First Academic Year-Autumn term: prerandomisation (baseline); Preintervention-Autumn Term: postpersonal mindfulness (MBCT-L) and school-based mindfulness training (SBMT) teacher training; Post intervention-Summer Term: after delivery of the SBMT to students; 1-yrF/U-Autumn Term: 1-year follow-up measure.

Figure 2

Teacher selection through the school-based mindfulness training. This represents teacher flow through the school-based mindfulness training (SBMT) and implementation, and is explained in the Methods and Results sections. Teacher attrition is shown in figure 1. Baseline for student data collection-autumn: prerandomisation (baseline); prestudent SBMT-autumn: postpersonal mindfulness (MBCT-L) and SBMT teacher training; post-student SBMT-summer: after delivery of the SBMT to students.


The study setting was UK secondary schools offering SEL in line with good practice.


Following collection of baseline data, schools were randomised (1:1) to trial arms based on computer generated random numbers. An independent statistician generated the allocation sequence, and the trial manager enrolled the clusters and assigned them to the trial arms. Allocation of schools was balanced on: school size (large (≥1000 children), small (<1000 children)); school quality (‘outstanding/good’, ‘requires improvement’); and deprivation (below/above the median percentage across all UK schools of children eligible for free school meals; 29.4%). For cohort 2, allocation was also balanced on type of school (boys, girls, mixed) and region (England, Scotland, Wales, Northern Ireland). Constrained randomisation21 was used, where the allocation sequence was randomly selected out of those with a high level of balance on the above factors between arms. Allocation concealment was achieved as all schools (and teachers) were recruited before randomisation and allocated en bloc for each cohort.17 18


SBMT programme

While the SBMT programme’s primary aim was to teach mindfulness skills that support young people’s resilience, its wider aims included enhancing teachers’ mental health and school climate. Informed by theory and implementation science,16 SBMT was designed to be integrated into the school curriculum. The process started with engaging the school leadership team, and then identifying a potential pool of teachers from within the school who could be trained and timetabled to deliver it to the students.

The full SBMT teacher training involved first participating in an 8-week personal mindfulness-based cognitive therapy for life (MBCT-L) programme. MBCT-L is an adaptation of the original MBCT programme which was developed for people with a history of recurrent depression.22 It is an 8-week, group-based (up to 15 participants), psychoeducational programme that integrates cognitive–behavioural strategies with MT. Each weekly session was 2 hours long and participants were asked to complete 40 min per day of mindfulness practice. The programme includes strategies and practices to stabilise attention, regulate emotions and behaviours, enhance self-care and transfer this learning into personal/professional domains. Sessions included guided mindfulness practices, weekly homework and teaching/discussion.

From the pool of teachers undergoing personal MT (MBCT-L), schools selected the sample of teachers to go forward with the SBMT. Senior leadership teams in schools based their selection on whether teachers would be willing and available to attend further training and could be timetabled to teach the SBMT to participating study classes. Selected teachers then attended a 4-day training workshop to learn how to deliver SBMT to students. Following this 4-day training, participating teachers taught the full SBMT curriculum to a group of non-participating pupils (non-study pupils) within the same school before delivering it to participating pupils (study pupils), with support from an experienced mentor, before going on to teach the study students.

Within participating schools, as many teachers as possible were invited to attend the personal MT (MBCT-L), to give schools the best opportunity to timetable the required number of teachers to teach the SBMT curriculum to study classes. Further embedding SBMT into the school included opening the training up to staff beyond the nominated teachers, helping schools integrate mindfulness into their school improvement plan and using mindfulness skills throughout the school curriculum.

Teaching as usual

The trial aim was to establish if SBMT is a potential alternative to current good SEL practice in secondary schools. Therefore, no additional teacher training or SEL was provided in the TAU arm. There is a large variety of SEL programmes23 and delivering SEL is rarely mandatory. In the UK, it is usually taught as part of ‘Personal, Social, Health and Economic Education’ intended to prepare students with the knowledge, skills and attributes they need to manage their lives. While SEL provision was not uniform in the TAU arm, TAU schools agreed not to provide other curricula that include MT until study completion. SEL provision was assessed using a bespoke tool based in part on existing measures (see online supplemental A and B for more details).

Supplemental material

Outcome measures

Outcomes were measured at the teacher level prerandomisation (baseline−T0), post personal MT (MBCT-L) and SBMT teacher training (or equivalent time in the TAU arm−T1), after delivery of the SBMT to students (T2), and 1-year follow-up after post personal MT (MBCT-L) and SBMT teacher training (2 years after baseline−T3).

Teacher mental health was assessed with the following measures: teachers’ burnout (Maslach Burnout Inventory-Educator Survey, MBI-ES, including exhaustion, depersonalisation and (lack of) personal accomplishment); self-efficacy (Teacher’s Self-Efficacy Scale, including student engagement, instructional practice and classroom management); mindfulness (Five Facet Mindfulness Questionnaire-Short Form); mindfulness in teaching (Mindfulness in Teaching Scale, including intrapersonal and interpersonal mindfulness); stress (Perceived Stress Scale, PSS); depression (Patient Health Questionnaire); and anxiety (Generalised Anxiety Disorder).

School climate was assessed with the School Climate and Connectedness Survey, using three scales most relevant to SBMT: ‘School Leadership and Involvement,’ ‘Staff Attitudes,’ and ‘Respectful Climate’. All participating study teachers (only those that participated in the trial) rated school climate, and the average teacher rating for each school was used.

We assessed the participating teachers’ engagement with the SBMT in two ways. First their personal MT (MBCT-L) was assessed through two self-report items asking about the frequency of formal (structured) and informal (flexible) mindfulness practice. Second, the extent to which participating teachers completed the full training/implementation route of the SBMT was recorded. Further details on the measures are in online supplemental A.

Statistical analysis

The analysis followed a prespecified plan. The sample size for the trial was justified on the basis of student outcomes,17 so no formal power calculations were undertaken regarding teacher outcomes.

Characteristics were summarised using means (SDs) for continuous variables and numbers (percentages) for categorical variables. Outcomes were compared between the trial arms using the intention-to-treat principle. Missing outcome data (assumed to be missing at random) were imputed using the multivariate linear mixed effects (‘multilevel’) model. The imputation model included the outcomes at each time point, trial arm, the stratification factors and other characteristics prespecified for covariate adjustment, the extent to which formal/informal mindfulness was practised, and the completion of the full training/implementation route of the SBMT, generating 20 imputed datasets.

Outcomes at each time point were compared using mixed effects linear regressions, allowing for correlation between observations from the same school (cluster). The main comparisons were adjusted for the factors used to balance the randomisation, study cohort, and the baseline score for the outcome. Means (SDs) were reported for each trial arm along with the crude mean difference between arms, the adjusted mean difference, the 95% CI and p value for the adjusted mean difference. The pooled intracluster correlation coefficient across the trial arms was reported for the outcomes from the crude (unadjusted) analysis. Results from the complete case analyses are also reported.

Additional post hoc sensitivity analyses utilising Complier Average Causal Effect (CACE)/instrumental variable methods24 were also undertaken to explore the causal effects of: (1) teacher engagement with the SBMT intervention and (2) regular formal/informal mindfulness practice. For the former, two definitions of compliance (engagement) were used: (1) attendance at a minimum of four personal MT (MBCT-L) sessions; and (2) attendance at a minimum of four personal MT (MBCT-L) sessions and the 4-day training course and delivery of at least one mindfulness session to students. For the assessment of the effects of both formal and informal mindfulness practice, three definitions of compliance (self-reported mindfulness practice) were used: (1) at least occasionally; (2) at least several times per week, and (3) daily. A two-stage least squares instrumental variable approach with cluster (school) robust standard errors was used to estimate these causal effects.24 Teacher gender, number of years teaching and preintervention stress (measured using PSS) were included at the first stage regression (to predict compliance), and adjustments for cohort, the factors used to balance the randomisation, and the preintervention value of the outcome were included at the second stage regression (to predict the outcome). Allocated group was used as the instrumental variable for each of the compliance definitions. All mean differences are presented with 95% CIs and p values. Unadjusted mean differences, without adjustment at either stage of the two-stage least squares model, are also reported.

Data were imputed and analysed using R (V.3.6.1),25 and Stata V.16.1, respectively.


We recruited 85 schools; 43 were randomised to SBMT and 42 to TAU. Six hundred seventy-nine teachers were recruited: 362 in the SBMT arm and 317 in the TAU arm. One school, including seven teachers, withdrew soon after randomisation because of the time commitment and was therefore excluded. As a result, 672 teachers (362 SBMT, 310 TAU) and 84 schools (43 SBMT, 41 TAU) were included in the analyses. Schools and teachers in both trial arms are described in table 1. Participating schools were broadly representative of UK schools (online supplemental B) with respect to the population served on key variables such as deprivation (ie, percentage of children eligible for free school meals), and the type of school (ie, selective/non-selective, urban/rural, large/small, mixed/single gender, state maintained/independent).19 26

Table 1

Preintervention school and teacher characteristics by trial arm status and overall

The number of schools and teachers that were lost to follow-up at each time point are reported in figure 1 (online supplemental tables S1–S3). Within the SBMT arm, there were teachers who did not progress through the full SBMT training/implementation, due to timetabling issues. Teachers across both arms were lost to follow-up through being off school (eg, maternity or sick leave), or teachers being otherwise unreachable. In general, teachers lost to follow-up were younger, had fewer years of teaching experience, were less likely to be White, and were more likely to be qualified teachers. Teachers lost to follow-up, compared with those who remained, were less likely to be female in the SBMT arm, but more likely to be female in the TAU arm (online supplemental tables S1–S3).

Teacher outcomes

Following their personal MT (MBCT-L) and teacher training, teachers in the SBMT arm reported greater student engagement (self-efficacy) than teachers in the TAU arm, but differences for the other two subscales were not significant (online supplemental table S4). After delivering the curriculum to students, teachers in the SBMT arm reported less burnout (emotional exhaustion and lack of personal accomplishment), but differences for depersonalisation were only significant when a minimum of attendance was present (online supplemental table S5). There was little evidence of a difference on other measures of mental health, perceived stress, self-efficacy, or mindfulness between teachers in the SBMT and TAU arms at either of these time points (online supplemental tables S4 and S5). At 1-year follow-up, there was only evidence of differences between teachers in the SBMT on mindfulness intrapersonal compared with teachers in the TAU arm (table 2).

Table 2

Main comparisons of teacher outcomes at 1-year follow-up

School outcomes

Following their personal MT (MBCT-L), teachers in the SBMT arm reported better school leadership and involvement than teachers in the TAU arm (online supplemental table S4). After delivering the SBMT to students, teachers in the SBMT arm continued to report better school climate in terms of leadership and involvement, but also in respectful climate (online supplemental table S5). At 1-year follow-up, teachers in the SBMT arm continued to report a more respectful climate than teachers in the TAU arm, but there were no differences in other dimensions of school climate (table 2).

Teachers’ engagement with the SBMT and outcomes

In the SBMT arm, 84% (305/362) of teachers attended personal MT (MBCT-L); while 44% (160/362) of teachers attended personal MT (MBCT-L) and SBMT teacher training. Regarding formal mindfulness practice at 1-year follow-up, 69% (140/204) practised mindfulness at least occasionally, 24% (48/204) at least several times a week and 4% (8/204) practised daily. For informal mindfulness practice at 1-year follow-up, 82% (167/204) practised mindfulness at least occasionally, 48% (97/204) at least several times a week and 18% (36/204) practised daily.

The results of the CACE/instrumental variable analyses represent estimation of the intervention effect among the subpopulation of compliers in the intervention arm, compared with those in the control arm who would have complied with the intervention, had they been offered it. The CACE analyses and the instrumental variable analyses indicated little evidence of a relationship between personal mindfulness (attendance at the 8-week MBCT-L course) (table 2, online supplemental tables S4 and S5) or formal or informal mindfulness (online supplemental tables S6–S11) and the outcomes. As with the ITT analysis, the only exceptions were intrapersonal mindfulness and respectful climate at 1 year, and burnout and school climate at post intervention.

Main comparisons of teacher outcomes using complete case analysis are provided in online supplemental tables S12–14.

Adverse events

Two serious adverse events were recorded. The independent Data Monitoring and Ethics Committee concluded that neither was attributable to the SBMT.


This study extends our earlier report of a universal SBMT compared with standard SEL on student mental health and well-being by focussing on teachers. SBMT, compared with usual provision, reduced teacher burnout with small effects. This finding is noteworthy as burnout is a significant hazard in the teaching profession.27 However, effects were not extended to other teacher outcomes and were not sustained at 1-year follow-up.

SBMT compared with TAU was associated with enhancements in school climate, at least as perceived by the teachers themselves. These differences in school climate in terms of respectful climate were maintained at 1-year follow-up with small-to-moderate effects. This is important because a positive school environment could create a cascade of effects, for example, improving teacher–student relationships and enabling more positive staff relationships.11 12 In contrast, a poor school climate may create a ‘burnout cascade’: job-related exhaustion, depersonalisation and demoralisation.13

This is a report of secondary outcomes of the MYRIAD trial and as such the findings are exploratory and subject to several limitations (eg, the multiple analyses may lead to statistical significance through chance alone). The school climate measure was a rating by study teachers, and not all teachers in the school; they may be subject to selection/demand effects. It would be interesting to crossvalidate this with wider perspectives, for example, teacher absenteeism. Finally, participating teachers reported above average mental health and this likely facilitated their SBMT entry. Engagement with mindfulness practice typically is associated with greater effects, but also people with better well-being may be less motivated to practice. It is important in interpreting and generalising the findings to consider which teachers are best placed to teach SEL.

Some SEL programmes are primarily student-oriented and hence effects on teacher mental health would likely be indirect. Others like this universal SBMT are intended to include school and teacher level effects, both directly through personal MT and indirectly through changes in school climate. Theoretical models that articulate how universal SEL programmes might create transformative and lasting change have been articulated,2 13 16 and now need systematic testing if we are to create schools that not only advance students’ academic learning but also support the well-being of the whole school community.

Clinical implications

The analyses reported in this paper indicate that SBMT might have promise in supporting changes in teacher burnout and school climate. However, innovation is required if broader effects are to manifest and be preserved.16 28

Data availability statement

Data are available upon reasonable request. The baseline data and codebook from the MYRIAD trial are available from Prof. Kuyken ( upon request (release of data is subject to an approved proposal and a signed data access agreement).

Ethics statements

Patient consent for publication

Ethics approval

This study involves human participants and was approved by University of Oxford Medical Sciences Division Ethics Committee (R45358; 23/05/2016). Participants gave informed consent to participate in the study before taking part.


The authors are very grateful of all the participating schools, teachers, and young people for giving their time so generously to participate in this project. We are grateful to the members of the Trial Steering Committee [Nick Axford (Chair), Chris Bonell, Sam Cartwright–Hatton, Cathy Creswell (previous Chair), Steve Hollon, Lucinda Powell, Paul Ramchandani (previous member), Paul Stallard, Una Sookun], Data Monitoring and Ethics Committee [Ruth Baer (previous member), Jan R. Boehnke, Mike Campbell (Chair), Sona Dimidjian, Judy Kidger, Obi Ukoumunne] and Scientific Advisory Board for the programme as a whole [Nick Allen, Susan Bogels, Pim Cuijpers, Celene Domitrovich, Uta Frith (Chair), Terrie Moffitt, Vikram Patel].


Supplementary materials

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.


  • OCU, MTG, TF, TD, SB and JMGW are joint senior authors.

  • Collaborators The MYRIAD Team Authorship comprises of Saz Ahmed, Marc Bennett, Katie Fletcher, Lucy Foulkes, Kirsty Griffiths, Cait Griffin, Konstantina Komninidou, Rachel Knight, Suzannah Laws, Jovita Leung, Jenna Parker, Blanca Piera Pi-Sunyer, Ashok Sakhardande, Elise Sellars, Maris Vainre, Lucy Warriner and Brian Wainman. These individuals have worked across the MYRIAD strategic award ‘Promoting Mental Health and Building Resilience in Adolescence: Investigating Mindfulness and Attentional Control’.

  • Contributors WK, JMGW, TD, OCU, TF, SBy and MTG were responsible for the original proposal and securing funding for the trial. WK, OCU, JMM, MA, BJ and SBa have verified the underlying data. WK as chief investigator had overall responsibility for the management of the study. WK, JMM, and OU, drafted the manuscript. WK, SBa, CC, PG, BJ, JMM, EN, AR, LT, KT, RMV, MA, LA, DD, TC, ND, KDW, ERF, JH, VH, NK, MK, LL, EM, LP, AP, AP, IPN, LR, AS, JS, AT, SJB, OCU, MTG, TF, TD, SBy, and JMGW read and approved the final manuscript. WK acts as guarantor.

  • Funding This research was funded in whole, or in part, by the Wellcome Trust (WT104908/Z/14/Z and WT107496/Z/15/Z) and supported by the National Institute for Health Research Clinical Research Network (NIHR CRN). For the purposes of Open Access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. Susan Ball, Ben Jones and Obi Ukoumunne were supported by the National Institute for Health Research (NIHR) Applied Research Collaboration South West Peninsula. JM-M has a “Miguel Servet” research contract from the ISCIII (CP21/00080).

  • Disclaimer The views expressed in this publication are those of the author(s) and not necessarily those of the National Institute for Health Research or the Department of Health and Social Care.

  • Competing interests WK is the Director of the Oxford Mindfulness Centre and receives royalties for several books on mindfulness. JMGW is former Director of the Oxford Mindfulness Centre and receives royalties for several books on mindfulness.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.