Most important non-serious AEs of patients and HCPs
| AEs | Probability (%) for each specific AE to be ranked higher than the AE considered the least important by patients (ie, cold symptoms) (95% CI) |
| The six most important AEs for patients | |
| Insomnia | 95.9 (95.2 to 96.5) |
| Anxiety | 95.2 (94.3 to 95.9) |
| Fatigue | 94.6 (93.6 to 95.4) |
| Weight gain | 93.2 (92.0 to 94.2) |
| Agitation | 92.7 (91.5 to 93.8) |
| Sexual dysfunction | 92.6 (91.4 to 93.8) |
| The six most important AEs for HCPs | |
| Sexual dysfunction | 99.2 (98.5 to 99.6) |
| Weight gain | 98.9 (97.7 to 99.4) |
| Erectile disorder | 98.8 (97.7 to 99.4) |
| Sleepiness | 98.8 (97.6 to 99.4) |
| Agitation | 98.4 (96.9 to 99.2) |
| Nausea | 98.3 (96.6 to 99.2) |
| Additional AEs reported in the free-text responses by more than 5% of patients and HCPs who answered the open-ended questions (n=1323) | Frequency (%) |
| Emotional numbing | 8.6 |
| Trouble with concentration | 7.6 |
| Irritability | 6 |
| Withdrawal syndrome | 5.9 |
AE, adverse event; HCP, healthcare professional.