Characteristics of patients (N=1631)
Patients (N=1631) | ||
n (%) | Missing | |
Gender | 0 | |
Female | 1290 (79.1) | |
Male | 312 (19.1) | |
Other | 29 (1.8) | |
Age (years), mean (SD) | 39.4 (13.0) | 1 (0.1) |
Min–max | 18–89 | |
Countries* | 16 (1) | |
France | 797 (48.9) | |
UK | 402 (24.6) | |
USA | 111 (6.8) | |
Canada | 107 (6.6) | |
Other (40 countries) | 198 (12.1) | |
Duration of education (years), mean (SD) | 17.1 (4.3) | 159 (9.7) |
Perceived wealth | 40 (2.5) | |
Living comfortably on present income | 445 (27.3) | |
Coping on present income | 605 (37.1) | |
Difficult on present income | 299 (18.3) | |
Very difficult on present income | 180 (11.0) | |
I prefer not to answer/I don't know | 62 (3.8) | |
PHQ-9 score | 1 (0.1) | |
Not depressed (<5) | 269 (16.5) | |
Mild (5–9) | 398 (24.4) | |
Moderate (10–14) | 358 (21.9) | |
Moderately severe (15–19) | 316 (19.4) | |
Severe (≥20) | 289 (17.7) | |
History of suicide attempt | 0 | |
Yes | 507 (31.1) | |
No | 1039 (63.7) | |
Prefer not to answer | 85 (5.2) | |
Antidepressant treatment | ||
Currently on antidepressant | 1139 (69.8) | |
Previously on antidepressant | 492 (30.2) | |
Prescriber of the last antidepressant | ||
Psychiatrist | 903 (55.6) | |
Family doctor/general practitioner | 681 (41.7) | |
Prescribing nurse | 11 (0.7) | |
Prescribing pharmacist | 32 (1.9) | |
Other (neurologist, rheumatologist or pain doctor) | 4 (0.3) | |
Number of antidepressants taken lifelong† | ||
1 | 514 (31.5) | |
2 | 317 (19.4) | |
3 | 230 (14.1) | |
4 | 181 (11.1) | |
5 or more | 389 (23.9) | |
Type of antidepressants taken lifelong‡ | ||
Fluoxetine | 638 (39.1) | |
Venlafaxine | 628 (38.5) | |
Sertraline | 602 (36.9) | |
Citalopram | 577 (35.4) | |
Escitalopram | 508 (31.2) | |
Paroxetine | 402 (24.7) | |
Mirtazapine | 262 (16.1) | |
Amitryptiline | 238 (14.6) | |
Duloxetine | 233 (14.3) | |
Exposure to antidepressants | 8 (0.5) | |
Less than 6 months | 148 (9.1) | |
Between 6 months and 1 year | 137 (8.4) | |
Between 1 year and 5 years | 589 (36.1) | |
More than 5 years | 745 (45.7) | |
I don't know | 4 (0.2) | |
Experience of AEs | 34 (2.1) | |
Yes | 1438 (88.2) | |
No | 71 (4.4) | |
Don’t know | 88 (5.4) | |
Change of treatment due to AEs | 79 (5.2) | |
Without medical advice | 248 (16.2) | |
With medical advice | 694 (45.5) | |
No change | 493 (32.3) | |
Prefer not to answer | 12 (0.8) |
*We report here only the countries representing more than 5% of the patients. The further 38 countries are reported in online supplemental material 6.
†Number of antidepressants reported by patients among the list of 41 antidepressants.
‡We only list antidepressants reported by >10% of the participants. The 31 other antidepressants are reported in online supplemental material 5. Some people may have taken several antidepressants: only participants who reported having experienced AEs (n=1438) or did not know if they experienced AEs (n=88) answered this question (n=1526).
AE, adverse event; PHQ-9, Patient Health Questionnaire-9 .