Placebo response for each symptom domain as estimated by self-report and clinician-rated scores
| Symptom domain | Overall | Self-report | Clinician-rated | |||
| o/k (n) | SMD (95% CI) | o/k (n) | SMD (95% CI) | o/k (n) | SMD (95% CI) | |
| GAD | 103/69 (7343) | −1.28 (−1.45 to −1.10) | 44/34 (3393) | −0.81 (−0.99 to −0.63) | 59/59 (6823) | −1.60 (−1.82 to −1.39) |
| Social anxiety | 49/28 (2899) | −0.88 (−1.01 to −0.75) | 42/28 (2899) | −0.86 (−1.00 to −0.72) | 7/7 (588) | −0.97 (−1.16 to −0.78) |
| Panic | 35/18 (1761) | −0.60 (−0.87 to −0.32) | 34/17 (1736) | −0.60 (−0.89 to −0.31) | 1/1 (25) | −0.53 (−0.48 to −0.58) |
| Specific phobias | 17/11 (1210) | −0.64 (−0.80 to −0.47) | 17/11 (1210) | −0.64 (−0.80 to −0.47) | – | – |
| PTSD | 43/20 (1194) | −1.62 (−2.07 to −1.17) | 34/20 (1194) | −1.68 (−2.15 to −1.22) | 9/9 (606) | −1.15 (−1.67 to −0.62) |
| OCD | 43/22 (1380) | −0.77 (−0.94 to −0.60) | 26/22 (1380) | −0.80 (−1.01 to −0.59) | 17/16 (913) | −0.68 (−0.82 to −0.54) |
GAD, generalised anxiety disorder; k, number of studies; n, sample size; o, number of outcomes; OCD, obsessive-compulsive disorder; PTSD, post-traumatic stress disorder; SMD, standardised mean difference.