Excess deaths in bipolar disorder
Total person-years of follow-up | Observed deaths, n | Expected deaths, n | Excess deaths, n (%) | PYLL-65, total years, n | Excess PYLL-65/100 person-years, n | PYLL-75, total years, n | Excess PYLL-75/100 person-years, n | |
Age group | All-cause mortality | |||||||
15–24 | 23 442 | 88 | 12 | 76 (86) | 3707 | 13.6 | 4567 | 16.7 |
25–34 | 78 640 | 323 | 56 | 267 (83) | 11 141 | 11.7 | 14 301 | 15.1 |
35–44 | 84 788 | 503 | 111 | 392 (78) | 12 685 | 11.7 | 17 705 | 16.3 |
45–54 | 95 016 | 1022 | 310 | 712 (70) | 15 101 | 11.1 | 25 271 | 18.6 |
55–64 | 95 500 | 1364 | 707 | 657 (48) | 6978 | 3.5 | 20 568 | 10.3 |
15–64 | 377 386 | 3300 | 1196 | 2104 (64) | 49 612 | 8.4 | 82 412 | 14.0 |
Age group | Mortality due to external causes* | |||||||
15–24 | 23 442 | 76 | 9 | 67 (88) | 3187 | 12.0 | 3927 | 14.7 |
25–34 | 78 640 | 252 | 34 | 218 (87) | 8963 | 9.9 | 11 493 | 12.7 |
35–44 | 84 788 | 292 | 40 | 252 (86) | 8099 | 8.2 | 11 269 | 11.4 |
45–54 | 95 016 | 368 | 60 | 308 (84) | 6868 | 6.1 | 11 348 | 10.0 |
55–64 | 95 500 | 285 | 70 | 215 (75) | 1954 | 1.5 | 5284 | 4.1 |
15–64 | 377 386 | 1273 | 212 | 1061 (83) | 29 072 | 6.4 | 43 321 | 9.5 |
Age group | Mortality due to somatic causes† | |||||||
15–24 | 23 442 | 12 | 3 | 9 (75) | 520 | 1.7 | 640 | 2.0 |
25–34 | 78 640 | 71 | 22 | 49 (69) | 2178 | 1.9 | 2808 | 2.5 |
35–44 | 84 788 | 211 | 71 | 140 (66) | 4586 | 3.6 | 6436 | 5.0 |
45–54 | 95 016 | 654 | 250 | 404 (62) | 8233 | 5.4 | 13 923 | 9.1 |
55–64 | 95 500 | 1079 | 637 | 442 (41) | 5024 | 2.1 | 15 284 | 6.6 |
15–64 | 377 386 | 2027 | 984 | 1043 (51) | 20 541 | 2.8 | 39 091 | 5.3 |
Number of deaths in individuals aged 15–64 years during 2004–2018. Age-specific mortality rates in the Finnish general population were used in calculating expected deaths for bipolar disorder. Excess deaths proportion is calculated as the number of excess deaths/observed deaths. Causes of death are defined according to the International Classification of Diseases, 10th revision.
*Excluding accidental alcohol poisoning.
†Including accidental alcohol poisoning.
PYLL, potential years of life lost.