Table 1
Results of the competing risk regressions with two variants of the UKBDRS
| Predictor | β | HR | 95% CI Lower Upper | P | |
| UKBDRS | |||||
| Age (years) | 0.178 | 1.194 | 1.184 | 1.206 | 2.1×10−296 |
| Parental history (yes) | 0.431 | 1.539 | 1.415 | 1.674 | 2.1×10−296 |
| Education (years) | −0.041 | 0.960 | 0.948 | 0.972 | 2.1×10−296 |
| Townsend deprivation (most deprived) | 0.228 | 1.256 | 1.153 | 1.367 | 2.1×10−296 |
| Diabetes (yes) | 0.536 | 1.710 | 1.528 | 1.914 | 2.1×10−296 |
| Depression (yes) | 0.556 | 1.744 | 1.593 | 1.909 | 2.1×10−296 |
| Stroke (yes) | 0.655 | 1.925 | 1.652 | 2.242 | 2.1×10−296 |
| Hypertensive (yes) | 0.159 | 1.173 | 1.082 | 1.271 | 2.1×10−296 |
| High cholesterol (yes) | 0.104 | 1.110 | 1.015 | 1.213 | 2.1×10−296 |
| Sex (male) | 0.169 | 1.184 | 1.099 | 1.275 | 2.3×10−2 |
| Lives alone (yes) | 0.141 | 1.151 | 1.058 | 1.253 | 1×10−3 |
| UKBDRS-APOE | |||||
| Age (years) | 0.185 | 1.204 | 1.191 | 1.217 | 2.1×10−296 |
| Parental history (yes) | 0.311 | 1.365 | 1.24 | 1.503 | 2.1×10−296 |
| Education (years) | −0.038 | 0.963 | 0.949 | 0.977 | 2.1×10−296 |
| Townsend deprivation (most deprived) | 0.247 | 1.28 | 1.16 | 1.412 | 2.1×10−296 |
| Diabetes (yes) | 0.526 | 1.692 | 1.479 | 1.936 | 2.1×10−296 |
| Depression (yes) | 0.567 | 1.763 | 1.587 | 1.959 | 2.1×10−296 |
| Stroke (yes) | 0.643 | 1.902 | 1.586 | 2.28 | 2.1×10−296 |
| Hypertensive (yes) | 0.190 | 1.209 | 1.101 | 1.326 | 2.1×10−296 |
| High cholesterol (yes) | 0.027 | 1.028 | 0.928 | 1.138 | 6×10−1 |
| Sex (male) | 0.164 | 1.179 | 1.082 | 1.284 | 7×10−3 |
| Lives alone (yes) | 0.137 | 1.146 | 1.039 | 1.264 | 2.1×10−296 |
| APOE4 genotype (yes) | 1.129 | 3.091 | 2.845 | 3.359 | 2.1×10−296 |
For each predictor, the β coefficient and hazard ratio (HR) are presented, along with the 95% confidence interval of the HR and the Bonferroni-Holmes corrected p value. 14-year baseline survival,
, is 0.9916195 for the UKBDRS model and 0.9945524 for the UKBDRS-APOE model.UKBDRS, UK Biobank Dementia Risk Score.
