Table 2

Effects for treatment on depressive symptomatology severity, remission and relapse rates

	k	N	Effect size		P value	95% PI	I² (95% CI)
	k	N	Hedges’ g (95% CI)	OR (95% CI)	P value	95% PI	I² (95% CI)
Depressive symptomatology	7	1024	0.50 (0.23 to 0.76)		0.004	−0.06 to 1.05	51.1 (0 to 79.2)
Rater
Clinician-rated	4	420	0.37 (−0.04 to 0.77)		0.064	−0.55 to 1.28	38.4 (0 to 79.0)
Self-reported	7	1024	0.48 (0.23 to 0.73)		0.004	0.02 to 0.94	45.5 (0 to 77.0)
Follow-up
1–12 months	3	702	0.36 (−0.30 to 1.02)		0.145	−3.00 to 3.72	66.9 (0 to 90.5)
≥12 months	3	702	0.02 (−0.09 to 0.12)		0.579	−0.94 to 0.98	0 (0 to 89.6)
Remission rates
Post-treatment	5	804		2.57 (1.71 to 3.87)	0.003	1.56 to 4.22	0 (0 to 79.2)
≥6 months follow-up	3	702		1.75 (1.21 to 2.53)	0.023	0.25 to 12.42	0 (0 to 89.6)
Relapse rates
Post-treatment	3	284		0.17 (0.01 to 4.83)	0.150	*	62.7 (0 to 89.3)
≥6 months follow-up	3	702		0.46 (0.21 to 1.03)	0.053	0.04 to 5.35	0 (0 to 89.6)

*PI is not reported for this outcome, as the estimate is too broad to be useful given the limited number of studies and considerable heterogeneity.
PI, prediction interval.