Table 1

Studies reporting on spontaneous movement disorders

StudyFEPScale and thresholdDyskinesia (%)*Parkinsonism (%)*Akathisia (%)*Dystonia (%)*Risk of bias
Aydemir et al 36 AIMS (S&K)23Moderate
Ayehu et al 37 AIMS (S&K), SAS ≥359Moderate
Bhandari et al 38 +AIMS (S&K)14Moderate
Caligiuri and Lohr39 AIMS ≥114High
Caligiuri and Lohr40 SAS37High
Carbon et al 41 +AIMS (S&K)06Moderate
Chatterjee et al 42 +SAS ≥1 TDS (S&K)117Moderate
Chong et al 43 +SAS ≥32.3High
Cortese et al 44 +SAS ≥3 ESRS-D ≥11318High
Cuesta et al 45 +SAS ≥4 BARS AIMS19.5Moderate
Cunningham Owens et al 46 AIMS36High
Gervin et al 47 +AIMS (S&K)10Moderate
Honer et al 48 +ESRS ≥24276Moderate
Honer et al 49 HK cohort+AIMS ≥1 SAS ≥11.211.9High
Honer et al 49 Canada cohort+AIMS ≥1 ESRS ≥2103515High
Fenn et al 50 AIMS (S&K) SHRS >101418Moderate
Jager51 +AIMS (S&K) SAS ≥3 BARS ≥2115.66Moderate
Kopala et al 52 +ESRS02815.6Moderate
Kopala et al 53 +ESRS ≥28880Moderate
Lee et al 54 +AIMS (S&K)0High
McCreadie and Ohaeri55 AIMS (S&K)0Moderate
McCreadie et al 56 AIMS (S&K) SAS ≥33515High
Ojagbemi et al 57 +ESRS ≥2318.230Moderate
Ojagbemi et al 58 +ESRS ≥231630Moderate
Peralta et al 59 MRS18.57Moderate
Peralta et al 60 AIMS (S&K) SAS ≥3 BARS ≥21624.54Moderate
Puri et al 61 +AIMS (S&K) SAS ≥3 BARS ≥21140High
Rybakowski et al 62 +SHRS ≥10823Moderate
  • *Number and percentage of patients positive for the specific movement disorder in each study, according to the threshold in that study.

  • AIMS, Abnormal Involuntary Movement Scale; BARS, Barnes Akathisia Rating Scale ; ESRS, Extrapyramidal Symptom Rating Scale; FEP, first-episode psychosis; HK, HongKong; MRS, Modified Rogers Scale; SAS, Simpson-Angus Scale for extrapyramidal side effects ; SHRS, St. Hans Rating Scale for extrapyramidal symptoms; S&K, Schooler & Kane severity criteria for definite tardive dyskinesia: a score of 2 on at least two items or a score of ≥3 on one item of the AIMS.