Placebo in medicineIs there logic in the placebo?
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Cited by (154)
Placebo effects in pain
2020, International Review of NeurobiologyCitation Excerpt :Within the 1950s, physicians and researchers began to acknowledge placebo as a confounding variable within experimental studies. Shortly after, placebos became defined by Gotzsche as “the difference in outcome between a placebo-treated group and an untreated control group in an unbiased experiment” (Gotzsche, 1994, 1995). It appears that the history of the placebos is not the history of the placebo effects, but rather is part of the history of medicine.
Do patients with cystic fibrosis participating in clinical trials demonstrate placebo response? A meta-analysis
2019, Journal of Cystic FibrosisCitation Excerpt :Our research was restricted to studies published in English or French. For each study included, the following information was extracted and entered in the database: [1] date of publication, [2] design of the study (randomisation, blinding, parallel group or cross-over), [3] duration of the study, [4] patients' characteristics (adults, children or both; sex, age, number of patients included in placebo and treatment arms), [5] the drug assessed and its therapeutic class, [6] drug doses, [7] change from baseline to the end of the study for three continuous outcomes in the placebo and treatment arms: FEV1, BMI,health-related quality of life outcomes with the respiratory domain of the CF questionnaire revised (CFQR-RD), [8] percentage of exacerbations during the study for each arm when available, [9] CF lung disease severity based on baseline FEV1 value when available, [10] CFTR gene mutations if given, [11] any adverse event in both arms if available as well as withdrawals for any adverse event and [12] concomitant treatments. Data were extracted independently by two authors (JC and VV) and then compared.
Effect of placebo acupuncture over no-treatment: A simple model incorporating the placebo and nocebo effects
2016, Complementary Therapies in MedicineTherapeutic efficacy. Between scientific medicine and healthcare medicine
2016, Presse Medicale