Detecting Alcohol-Induced Brain Damage Noninvasively Using Diffusion Tensor Imaging

ACS Chem Neurosci. 2019 Oct 16;10(10):4187-4189. doi: 10.1021/acschemneuro.9b00481. Epub 2019 Sep 12.

Abstract

While alcohol's detrimental effects on the brain are widely acknowledged, diagnostic markers for detection and monitoring alcohol-induced brain damage are lacking. A recent study showed that diffusion tensor imaging can be used to monitor this damage and characterized the progression of the observed changes into early abstinence. Here, we discuss the main findings of that study and highlight current technical limitations which, once addressed, can pave the way to the development of new powerful diagnostic markers for alcohol-induced brain damage.

Keywords: Alcohol; DTI; brain damage; diagnostic marker; gray matter; white matter.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / diagnostic imaging*
  • Brain / drug effects
  • Brain / pathology
  • Brain Diseases / chemically induced
  • Brain Diseases / diagnostic imaging*
  • Brain Diseases / pathology
  • Diffusion Tensor Imaging*
  • Ethanol / adverse effects*
  • Humans

Substances

  • Ethanol